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Phylogenetic profiling resolves early emergence of PRC2 and illuminates its functional core
Polycomb repressive complex 2 (PRC2) is involved in maintaining transcriptionally silent chromatin states through methylating lysine 27 of histone H3 by the catalytic subunit enhancer of zeste [E(z)]. Here, we report the diversity of PRC2 core subunit proteins in different eukaryotic supergroups wit...
Autores principales: | Sharaf, Abdoallah, Vijayanathan, Mallika, Oborník, Miroslav, Mozgová, Iva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018016/ https://www.ncbi.nlm.nih.gov/pubmed/35440471 http://dx.doi.org/10.26508/lsa.202101271 |
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