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Patient-specific Boolean models of signalling networks guide personalised treatments

Prostate cancer is the second most occurring cancer in men worldwide. To better understand the mechanisms of tumorigenesis and possible treatment responses, we developed a mathematical model of prostate cancer which considers the major signalling pathways known to be deregulated. We personalised thi...

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Detalles Bibliográficos
Autores principales: Montagud, Arnau, Béal, Jonas, Tobalina, Luis, Traynard, Pauline, Subramanian, Vigneshwari, Szalai, Bence, Alföldi, Róbert, Puskás, László, Valencia, Alfonso, Barillot, Emmanuel, Saez-Rodriguez, Julio, Calzone, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018074/
https://www.ncbi.nlm.nih.gov/pubmed/35164900
http://dx.doi.org/10.7554/eLife.72626