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α-Lipoic Acid-Plus Ameliorates Endothelial Injury by Inhibiting the Apoptosis Pathway Mediated by Intralysosomal Cathepsins in an In Vivo and In Vitro Endothelial Injury Model

α-Lipoic acid-plus (LAP), an amine derivative of α-lipoic acid, has been reported to protect cells from oxidative stress damage by reacting with lysosomal iron and is more powerful than desferrioxamine (DFO). However, the role of LAP in experimental carotid artery intimal injury (CAII) has not yet b...

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Detalles Bibliográficos
Autores principales: Wang, Yang, Bao, Dejun, Dong, Yongfei, Wei, Xiangpin, Yu, Jian, Niu, Chaoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018191/
https://www.ncbi.nlm.nih.gov/pubmed/35450412
http://dx.doi.org/10.1155/2022/8979904