Cargando…
α-Lipoic Acid-Plus Ameliorates Endothelial Injury by Inhibiting the Apoptosis Pathway Mediated by Intralysosomal Cathepsins in an In Vivo and In Vitro Endothelial Injury Model
α-Lipoic acid-plus (LAP), an amine derivative of α-lipoic acid, has been reported to protect cells from oxidative stress damage by reacting with lysosomal iron and is more powerful than desferrioxamine (DFO). However, the role of LAP in experimental carotid artery intimal injury (CAII) has not yet b...
Autores principales: | Wang, Yang, Bao, Dejun, Dong, Yongfei, Wei, Xiangpin, Yu, Jian, Niu, Chaoshi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018191/ https://www.ncbi.nlm.nih.gov/pubmed/35450412 http://dx.doi.org/10.1155/2022/8979904 |
Ejemplares similares
-
Risk Factors for Cerebral Infarction After Moderate or Severe Traumatic Brain Injury
por: Wu, Yin-gang, et al.
Publicado: (2021) -
Shunt-Dependent Post-Traumatic Hydrocephalus: Predictors and Long-Term Functional Outcomes
por: Xu, Hao, et al.
Publicado: (2023) -
α-lipoic acid protects against hypoxia/reoxygenation-induced injury in human umbilical vein endothelial cells through suppression of apoptosis and autophagy
por: ZHANG, JINGJING, et al.
Publicado: (2015) -
Effect of weak bases on the intralysosomal pH in mouse peritoneal macrophages
Publicado: (1981) -
An Intralysosomal hsp70 Is Required for a Selective Pathway of Lysosomal Protein Degradation
por: Agarraberes, Fernando A., et al.
Publicado: (1997)