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Antiretroviral drug exposure in lymph nodes is heterogeneous and drug dependent

INTRODUCTION: HIV reservoirs and infected cells may persist in tissues with low concentrations of antiretrovirals (ARVs). Traditional pharmacology methods cannot assess variability in ARV concentrations within morphologically complex tissues, such as lymph nodes (LNs). We evaluated the distribution...

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Detalles Bibliográficos
Autores principales: Rosen, Elias P., Deleage, Claire, White, Nicole, Sykes, Craig, Brands, Catherine, Adamson, Lourdes, Luciw, Paul, Estes, Jacob D., Kashuba, Angela D. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018350/
https://www.ncbi.nlm.nih.gov/pubmed/35441468
http://dx.doi.org/10.1002/jia2.25895