Thermodynamics-based modeling reveals regulatory effects of indirect transcription factor-DNA binding

Transcription factors (TFs) influence gene expression by binding to DNA, yet experimental data suggests that they also frequently bind regulatory DNA indirectly by interacting with other DNA-bound proteins. Here, we used a data modeling approach to test if such indirect binding by TFs plays a signif...

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Detalles Bibliográficos
Autores principales: Bhogale, Shounak, Sinha, Saurabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018382/
https://www.ncbi.nlm.nih.gov/pubmed/35465052
http://dx.doi.org/10.1016/j.isci.2022.104152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018382/
https://www.ncbi.nlm.nih.gov/pubmed/35465052
http://dx.doi.org/10.1016/j.isci.2022.104152

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