Nitric oxide precipitates catastrophic chromosome fragmentation by bolstering both hydrogen peroxide and Fe(II) Fenton reactants in E. coli

Immune cells kill invading microbes by producing reactive oxygen and nitrogen species, primarily hydrogen peroxide (H(2)O(2)) and nitric oxide (NO). We previously found that NO inhibits catalases in Escherichia coli, stabilizing H(2)O(2) around treated cells and promoting catastrophic chromosome fra...

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Detalles Bibliográficos
Autores principales: Agashe, Pooja, Kuzminov, Andrei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018393/
https://www.ncbi.nlm.nih.gov/pubmed/35288189
http://dx.doi.org/10.1016/j.jbc.2022.101825

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018393/
https://www.ncbi.nlm.nih.gov/pubmed/35288189
http://dx.doi.org/10.1016/j.jbc.2022.101825

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