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Nitric oxide precipitates catastrophic chromosome fragmentation by bolstering both hydrogen peroxide and Fe(II) Fenton reactants in E. coli
Immune cells kill invading microbes by producing reactive oxygen and nitrogen species, primarily hydrogen peroxide (H(2)O(2)) and nitric oxide (NO). We previously found that NO inhibits catalases in Escherichia coli, stabilizing H(2)O(2) around treated cells and promoting catastrophic chromosome fra...
Autores principales: | Agashe, Pooja, Kuzminov, Andrei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018393/ https://www.ncbi.nlm.nih.gov/pubmed/35288189 http://dx.doi.org/10.1016/j.jbc.2022.101825 |
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