Measles-based Zika vaccine induces long-term immunity and requires NS1 antibodies to protect the female reproductive tract

Zika virus (ZIKV) can cause devastating effects in the unborn fetus of pregnant women. To develop a candidate vaccine that can protect human fetuses, we generated a panel of live measles vaccine (MV) vectors expressing ZIKV-E and -NS1. Our MV-based ZIKV-E vaccine, MV-E2, protected mice from the non-...

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Detalles Bibliográficos
Autores principales: Kurup, Drishya, Wirblich, Christoph, Lambert, Rachael, Diba, Leila Zabihi, Leiby, Benjamin E., Schnell, Matthias J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018676/
https://www.ncbi.nlm.nih.gov/pubmed/35440656
http://dx.doi.org/10.1038/s41541-022-00464-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018676/
https://www.ncbi.nlm.nih.gov/pubmed/35440656
http://dx.doi.org/10.1038/s41541-022-00464-2

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