Magic angle spinning NMR structure of human cofilin-2 assembled on actin filaments reveals isoform-specific conformation and binding mode

Actin polymerization dynamics regulated by actin-binding proteins are essential for various cellular functions. The cofilin family of proteins are potent regulators of actin severing and filament disassembly. The structural basis for cofilin-isoform-specific severing activity is poorly understood as...

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Detalles Bibliográficos
Autores principales: Kraus, Jodi, Russell, Ryan W., Kudryashova, Elena, Xu, Chaoyi, Katyal, Nidhi, Perilla, Juan R., Kudryashov, Dmitri S., Polenova, Tatyana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018683/
https://www.ncbi.nlm.nih.gov/pubmed/35440100
http://dx.doi.org/10.1038/s41467-022-29595-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018683/
https://www.ncbi.nlm.nih.gov/pubmed/35440100
http://dx.doi.org/10.1038/s41467-022-29595-9

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