Structures of distant diphtheria toxin homologs reveal functional determinants of an evolutionarily conserved toxin scaffold

Diphtheria toxin (DT) is the archetype for bacterial exotoxins implicated in human diseases and has played a central role in defining the field of toxinology since its discovery in 1888. Despite being one of the most extensively characterized bacterial toxins, the origins and evolutionary adaptation...

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Detalles Bibliográficos
Autores principales: Sugiman-Marangos, Seiji N., Gill, Shivneet K., Mansfield, Michael J., Orrell, Kathleen E., Doxey, Andrew C., Melnyk, Roman A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018708/
https://www.ncbi.nlm.nih.gov/pubmed/35440624
http://dx.doi.org/10.1038/s42003-022-03333-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018708/
https://www.ncbi.nlm.nih.gov/pubmed/35440624
http://dx.doi.org/10.1038/s42003-022-03333-9

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