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An evolutionarily conserved stop codon enrichment at the 5′ ends of mammalian piRNAs

PIWI-interacting RNAs (piRNAs) are small RNAs required to recognize and silence transposable elements. The 5’ ends of mature piRNAs are defined through cleavage of long precursor transcripts, primarily by Zucchini (Zuc). Zuc-dependent cleavage typically occurs immediately upstream of a uridine. Howe...

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Detalles Bibliográficos
Autores principales: Bornelöv, Susanne, Czech, Benjamin, Hannon, Gregory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018710/
https://www.ncbi.nlm.nih.gov/pubmed/35440552
http://dx.doi.org/10.1038/s41467-022-29787-3