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An evolutionarily conserved stop codon enrichment at the 5′ ends of mammalian piRNAs
PIWI-interacting RNAs (piRNAs) are small RNAs required to recognize and silence transposable elements. The 5’ ends of mature piRNAs are defined through cleavage of long precursor transcripts, primarily by Zucchini (Zuc). Zuc-dependent cleavage typically occurs immediately upstream of a uridine. Howe...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018710/ https://www.ncbi.nlm.nih.gov/pubmed/35440552 http://dx.doi.org/10.1038/s41467-022-29787-3 |