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Cooperative interaction between ERα and the EMT-inducer ZEB1 reprograms breast cancer cells for bone metastasis

The epithelial to mesenchymal transition (EMT) has been proposed to contribute to the metastatic spread of breast cancer cells. EMT-promoting transcription factors determine a continuum of different EMT states. In contrast, estrogen receptor α (ERα) helps to maintain the epithelial phenotype of brea...

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Detalles Bibliográficos
Autores principales: Mohammadi Ghahhari, Nastaran, Sznurkowska, Magdalena K., Hulo, Nicolas, Bernasconi, Lilia, Aceto, Nicola, Picard, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018728/
https://www.ncbi.nlm.nih.gov/pubmed/35440541
http://dx.doi.org/10.1038/s41467-022-29723-5