Brain radiotherapy, tremelimumab-mediated CTLA-4-directed blockade +/− trastuzumab in patients with breast cancer brain metastases

Breast cancer brain metastases (BCBM) are a common and devastating complication of metastatic breast cancer with conventional systemic therapies demonstrating limited effectiveness. Consequently, radiotherapy (RT) ± surgery remains the cornerstone of BCBM management. Because preclinical and clinical...

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Detalles Bibliográficos
Autores principales: Page, David B., Beal, Kathryn, Linch, Stefanie N., Spinelli, Kateri J., Rodine, Micaela, Halpenny, Darragh, Modi, Shanu, Patil, Sujata, Young, Robert J., Kaley, Thomas, Merghoub, Taha, Redmond, David, Wong, Phillip, Barker, Christopher A., Diab, Adi, Norton, Larry, McArthur, Heather L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018738/
https://www.ncbi.nlm.nih.gov/pubmed/35440655
http://dx.doi.org/10.1038/s41523-022-00404-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018738/
https://www.ncbi.nlm.nih.gov/pubmed/35440655
http://dx.doi.org/10.1038/s41523-022-00404-2

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