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Dehydroepiandrosterone exacerbates nigericin-induced abnormal autophagy and pyroptosis via GPER activation in LPS-primed macrophages

As a widely acknowledged FDA-approved dietary supplement or over-the-counter medicines, dehydroepiandrosterone (DHEA) exerts anti-inflammatory and immunomodulatory function. Pyroptosis is an important form of programmed cell death (PCD), and which acts a key role in the body’s anti-infection and inf...

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Detalles Bibliográficos
Autores principales: Cao, Ji, Li, Longlong, Yao, Yao, Xing, Yuxiao, Ma, Haitian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018772/
https://www.ncbi.nlm.nih.gov/pubmed/35440074
http://dx.doi.org/10.1038/s41419-022-04841-6