Cargando…
Dehydroepiandrosterone exacerbates nigericin-induced abnormal autophagy and pyroptosis via GPER activation in LPS-primed macrophages
As a widely acknowledged FDA-approved dietary supplement or over-the-counter medicines, dehydroepiandrosterone (DHEA) exerts anti-inflammatory and immunomodulatory function. Pyroptosis is an important form of programmed cell death (PCD), and which acts a key role in the body’s anti-infection and inf...
Autores principales: | Cao, Ji, Li, Longlong, Yao, Yao, Xing, Yuxiao, Ma, Haitian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018772/ https://www.ncbi.nlm.nih.gov/pubmed/35440074 http://dx.doi.org/10.1038/s41419-022-04841-6 |
Ejemplares similares
-
Co-delivery of nigericin and decitabine using hexahistidine-metal nanocarriers for pyroptosis-induced immunotherapeutics
por: Niu, Qiang, et al.
Publicado: (2022) -
Nigericin Promotes NLRP3-Independent Bacterial Killing in Macrophages
por: Armstrong, Heather, et al.
Publicado: (2019) -
Nigericin Boosts Anti-Tumor Immune Response via Inducing Pyroptosis in Triple-Negative Breast Cancer
por: Wu, Lisha, et al.
Publicado: (2023) -
Approach to nigericin derivatives and their therapeutic potential
por: Sahu, Amit Kumar, et al.
Publicado: (2020) -
The sex steroid precursor dehydroepiandrosterone prevents nonalcoholic steatohepatitis by activating the AMPK pathway mediated by GPR30
por: Li, Longlong, et al.
Publicado: (2021)