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Single cell analyses identify a highly regenerative and homogenous human CD34+ hematopoietic stem cell population
The heterogeneous nature of human CD34(+) hematopoietic stem cells (HSCs) has hampered our understanding of the cellular and molecular trajectories that HSCs navigate during lineage commitment. Using various platforms including single cell RNA-sequencing and extensive xenotransplantation, we have un...
Autores principales: | Anjos-Afonso, Fernando, Buettner, Florian, Mian, Syed A., Rhys, Hefin, Perez-Lloret, Jimena, Garcia-Albornoz, Manuel, Rastogi, Namrata, Ariza-McNaughton, Linda, Bonnet, Dominique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018830/ https://www.ncbi.nlm.nih.gov/pubmed/35440586 http://dx.doi.org/10.1038/s41467-022-29675-w |
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