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Bipartite network models to design combination therapies in acute myeloid leukaemia

Combination therapy is preferred over single-targeted monotherapies for cancer treatment due to its efficiency and safety. However, identifying effective drug combinations costs time and resources. We propose a method for identifying potential drug combinations by bipartite network modelling of pati...

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Detalles Bibliográficos
Autores principales: Jafari, Mohieddin, Mirzaie, Mehdi, Bao, Jie, Barneh, Farnaz, Zheng, Shuyu, Eriksson, Johanna, Heckman, Caroline A., Tang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018865/
https://www.ncbi.nlm.nih.gov/pubmed/35440130
http://dx.doi.org/10.1038/s41467-022-29793-5