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NOX activation in reactive astrocytes regulates astrocytic LCN2 expression and neurodegeneration
Reactive astrocytes (RA) secrete lipocalin-2 (LCN2) glycoprotein that regulates diverse cellular processes including cell death/survival, inflammation, iron delivery and cell differentiation. Elevated levels of LCN2 are considered as a biomarker of brain injury, however, the underlying regulatory me...
Autores principales: | Liu, Ruijia, Wang, Jun, Chen, Yang, Collier, Jenelle M., Capuk, Okan, Jin, Shijie, Sun, Ming, Mondal, Sujan K., Whiteside, Theresa L., Stolz, Donna B., Yang, Yongjie, Begum, Gulnaz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018876/ https://www.ncbi.nlm.nih.gov/pubmed/35440572 http://dx.doi.org/10.1038/s41419-022-04831-8 |
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