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Cavβ1 regulates T cell expansion and apoptosis independently of voltage-gated Ca(2+) channel function
TCR stimulation triggers Ca(2+) signals that are critical for T cell function and immunity. Several pore-forming α and auxiliary β subunits of voltage-gated Ca(2+) channels (VGCC) were reported in T cells, but their mechanism of activation remains elusive and their contribution to Ca(2+) signaling i...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018955/ https://www.ncbi.nlm.nih.gov/pubmed/35440113 http://dx.doi.org/10.1038/s41467-022-29725-3 |