Cavβ1 regulates T cell expansion and apoptosis independently of voltage-gated Ca(2+) channel function

TCR stimulation triggers Ca(2+) signals that are critical for T cell function and immunity. Several pore-forming α and auxiliary β subunits of voltage-gated Ca(2+) channels (VGCC) were reported in T cells, but their mechanism of activation remains elusive and their contribution to Ca(2+) signaling i...

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Detalles Bibliográficos
Autores principales: Erdogmus, Serap, Concepcion, Axel R., Yamashita, Megumi, Sidhu, Ikjot, Tao, Anthony Y., Li, Wenyi, Rocha, Pedro P., Huang, Bonnie, Garippa, Ralph, Lee, Boram, Lee, Amy, Hell, Johannes W., Lewis, Richard S., Prakriya, Murali, Feske, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9018955/
https://www.ncbi.nlm.nih.gov/pubmed/35440113
http://dx.doi.org/10.1038/s41467-022-29725-3

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