Analysis of sub-kilobase chromatin topology reveals nano-scale regulatory interactions with variable dependence on cohesin and CTCF

Enhancers and promoters predominantly interact within large-scale topologically associating domains (TADs), which are formed by loop extrusion mediated by cohesin and CTCF. However, it is unclear whether complex chromatin structures exist at sub-kilobase-scale and to what extent fine-scale regulator...

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Detalles Bibliográficos
Autores principales: Aljahani, Abrar, Hua, Peng, Karpinska, Magdalena A., Quililan, Kimberly, Davies, James O. J., Oudelaar, A. Marieke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019034/
https://www.ncbi.nlm.nih.gov/pubmed/35440598
http://dx.doi.org/10.1038/s41467-022-29696-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019034/
https://www.ncbi.nlm.nih.gov/pubmed/35440598
http://dx.doi.org/10.1038/s41467-022-29696-5

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