Flubendazole induces mitochondrial dysfunction and DRP1-mediated mitophagy by targeting EVA1A in breast cancer

Breast cancer is still one of the most common malignancies worldwide and remains a major clinical challenge. We previously reported that the anthelmintic drug flubendazole induced autophagy and apoptosis via upregulation of eva-1 homolog A (EVA1A) in triple-negative breast cancer (TNBC) and was repu...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhen, Yongqi, Yuan, Zhaoxin, Zhang, Jiahui, Chen, Yao, Fu, Yuning, Liu, Yi, Fu, Leilei, Zhang, Lan, Zhou, Xian-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019038/
https://www.ncbi.nlm.nih.gov/pubmed/35440104
http://dx.doi.org/10.1038/s41419-022-04823-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019038/
https://www.ncbi.nlm.nih.gov/pubmed/35440104
http://dx.doi.org/10.1038/s41419-022-04823-8

Ejemplares similares