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Flubendazole induces mitochondrial dysfunction and DRP1-mediated mitophagy by targeting EVA1A in breast cancer
Breast cancer is still one of the most common malignancies worldwide and remains a major clinical challenge. We previously reported that the anthelmintic drug flubendazole induced autophagy and apoptosis via upregulation of eva-1 homolog A (EVA1A) in triple-negative breast cancer (TNBC) and was repu...
Autores principales: | Zhen, Yongqi, Yuan, Zhaoxin, Zhang, Jiahui, Chen, Yao, Fu, Yuning, Liu, Yi, Fu, Leilei, Zhang, Lan, Zhou, Xian-Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019038/ https://www.ncbi.nlm.nih.gov/pubmed/35440104 http://dx.doi.org/10.1038/s41419-022-04823-8 |
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