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Structural insights into the peptide selectivity and activation of human neuromedin U receptors

Neuromedin U receptors (NMURs), including NMUR1 and NMUR2, are a group of G(q/11)-coupled G protein-coupled receptors (GPCRs). NMUR1 and NMUR2 play distinct, pleiotropic physiological functions in peripheral tissues and in the central nervous system (CNS), respectively, according to their distinct t...

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Detalles Bibliográficos
Autores principales: You, Chongzhao, Zhang, Yumu, Xu, Peiyu, Huang, Sijie, Yin, Wanchao, Eric Xu, H., Jiang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019041/
https://www.ncbi.nlm.nih.gov/pubmed/35440625
http://dx.doi.org/10.1038/s41467-022-29683-w