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Insulin action and resistance are dependent on a GSK3β-FBXW7-ERRα transcriptional axis

Insulin resistance, a harbinger of the metabolic syndrome, is a state of compromised hormonal response resulting from the dysregulation of a wide range of insulin-controlled cellular processes. However, how insulin affects cellular energy metabolism via long-term transcriptional regulation and wheth...

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Detalles Bibliográficos
Autores principales: Xia, Hui, Scholtes, Charlotte, Dufour, Catherine R., Ouellet, Carlo, Ghahremani, Majid, Giguère, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019090/
https://www.ncbi.nlm.nih.gov/pubmed/35440636
http://dx.doi.org/10.1038/s41467-022-29722-6