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Insulin action and resistance are dependent on a GSK3β-FBXW7-ERRα transcriptional axis
Insulin resistance, a harbinger of the metabolic syndrome, is a state of compromised hormonal response resulting from the dysregulation of a wide range of insulin-controlled cellular processes. However, how insulin affects cellular energy metabolism via long-term transcriptional regulation and wheth...
Autores principales: | Xia, Hui, Scholtes, Charlotte, Dufour, Catherine R., Ouellet, Carlo, Ghahremani, Majid, Giguère, Vincent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019090/ https://www.ncbi.nlm.nih.gov/pubmed/35440636 http://dx.doi.org/10.1038/s41467-022-29722-6 |
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