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xCT contributes to colorectal cancer tumorigenesis through upregulation of the MELK oncogene and activation of the AKT/mTOR cascade

Colorectal cancer (CRC) is one of the most commonly diagnosed and deadly malignant tumors globally, and its occurrence and progression are closely related to the poor histological features and complex molecular characteristics among patients. It is urgent to identify specific biomarkers for effectiv...

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Detalles Bibliográficos
Autores principales: Tang, Bufu, Zhu, Jinyu, Liu, Fangming, Ding, Jiayi, Wang, Yajie, Fang, Shiji, zheng, Liyun, Qiu, Rongfang, Chen, Minjiang, Shu, Gaofeng, Xu, Min, Lu, Chenying, Zhao, Zhongwei, Yang, Yang, Ji, Jiansong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019093/
https://www.ncbi.nlm.nih.gov/pubmed/35440604
http://dx.doi.org/10.1038/s41419-022-04827-4