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The genetic architecture of target‐site resistance to pyrethroid insecticides in the African malaria vectors Anopheles gambiae and Anopheles coluzzii

Resistance to pyrethroid insecticides is a major concern for malaria vector control. Pyrethroids target the voltage‐gated sodium channel (VGSC), an essential component of the mosquito nervous system. Substitutions in the amino acid sequence can induce a resistance phenotype. We use whole‐genome sequ...

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Detalles Bibliográficos
Autores principales: Clarkson, Chris S., Miles, Alistair, Harding, Nicholas J., O’Reilly, Andrias O., Weetman, David, Kwiatkowski, Dominic, Donnelly, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019111/
https://www.ncbi.nlm.nih.gov/pubmed/33590926
http://dx.doi.org/10.1111/mec.15845