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Germline variants in cancer therapy

Cancer pharmacogenetics implies a complex combination of germline variants from the patient and somatic mutations in tumor cells. Somatic mutations meanwhile have become drugable targets or biomarkers, whereas germline mutations potentially predict adverse drug effects or drug response. Here, we eva...

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Detalles Bibliográficos
Autores principales: Kaehler, Meike, Cascorbi, Ingolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019177/
https://www.ncbi.nlm.nih.gov/pubmed/35582146
http://dx.doi.org/10.20517/cdr.2019.05