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The use of pharmacogenetics to increase the safety of colorectal cancer patients treated with fluoropyrimidines

Fluoropyrimidines (FP) are given in the combination treatment of the advanced disease or as monotherapy in the neo-adjuvant and adjuvant treatment of colorectal cancerand other solid tumors including breast, head and neck and gastric cancer. FP present a narrow therapeutic index with 10 to 26% of pa...

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Detalles Bibliográficos
Autores principales: De Mattia, Elena, Roncato, Rossana, Dalle Fratte, Chiara, Ecca, Fabrizio, Toffoli, Giuseppe, Cecchin, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019179/
https://www.ncbi.nlm.nih.gov/pubmed/35582139
http://dx.doi.org/10.20517/cdr.2019.04