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Oxidative stress and redox signaling in CRPC progression: therapeutic potential of clinically-tested Nrf2-activators

Androgen deprivation therapy (ADT) is the mainstay regimen in patients with androgen-dependent prostate cancer (PCa). However, the selection of androgen-independent cancer cells leads to castrate resistant prostate cancer (CRPC). The aggressive phenotype of CRPC cells underscores the need to elucida...

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Detalles Bibliográficos
Autores principales: Mondal, Debasis, Narwani, Devin, Notta, Shahnawaz, Ghaffar, Dawood, Mardhekar, Nikhil, Quadri, Syed S. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019181/
https://www.ncbi.nlm.nih.gov/pubmed/35582006
http://dx.doi.org/10.20517/cdr.2020.71