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Evaluation of the reducing potential of PSMA-containing endosomes by FRET imaging

Aim: Ligand-targeted therapeutics are experiencing increasing use for treatment of human diseases due to their ability to concentrate a desired drug at a pathologic site while reducing accumulation in healthy tissues. For many ligand-targeted drug conjugates, a critical aspect of conjugate design li...

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Detalles Bibliográficos
Autores principales: Venkatesh, Chelvam, Shen, Jiayin, Putt, Karson S., Low, Philip S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019189/
https://www.ncbi.nlm.nih.gov/pubmed/35582012
http://dx.doi.org/10.20517/cdr.2020.84