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The bone marrow microenvironment as a mediator of chemoresistance in acute lymphoblastic leukemia
Acute lymphoblastic leukemia (ALL) is a malignancy of immature lymphoid cells that arises due to clonal expansion of cells that undergo developmental arrest and acquisition of pathogenic mutations. With the introduction of intensive multi-agent chemotherapeutic regimens, survival rates for ALL have...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
OAE Publishing Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019215/ https://www.ncbi.nlm.nih.gov/pubmed/35582273 http://dx.doi.org/10.20517/cdr.2019.63 |