Inhibition of PDE10A-Rescued TBI-Induced Neuroinflammation and Apoptosis through the cAMP/PKA/NLRP3 Pathway

Phosphodiesterase 10A (PDE10A) is a dual-substrate phosphodiesterase that is highly expressed in the striatal complex. PDE10A is an important target for the treatment of ganglion dysfunction and neuroinflammation-related diseases, but its possible impact on traumatic brain injury (TBI) is still uncl...

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Detalles Bibliográficos
Autores principales: Huang, Jin, Tang, Dang, Cao, Yiqiang, Wang, Yonggang, Long, Jiang, Wei, Lin, Song, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019408/
https://www.ncbi.nlm.nih.gov/pubmed/35463083
http://dx.doi.org/10.1155/2022/3311250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019408/
https://www.ncbi.nlm.nih.gov/pubmed/35463083
http://dx.doi.org/10.1155/2022/3311250

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