Seamless Gene Correction in the Human Cystic Fibrosis Transmembrane Conductance Regulator Locus by Vector Replacement and Vector Insertion Events

Background: Gene correction via homology directed repair (HDR) in patient-derived induced pluripotent stem (iPS) cells for regenerative medicine are becoming a more realistic approach to develop personalized and mutation-specific therapeutic strategies due to current developments in gene editing and...

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Detalles Bibliográficos
Autores principales: Suzuki, Shingo, Chosa, Keisuke, Barillà, Cristina, Yao, Michael, Zuffardi, Orsetta, Kai, Hirofumi, Shuto, Tsuyoshi, Suico, Mary Ann, Kan, Yuet W., Sargent, R. Geoffrey, Gruenert, Dieter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genome Editing
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019469/
https://www.ncbi.nlm.nih.gov/pubmed/35465025
http://dx.doi.org/10.3389/fgeed.2022.843885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019469/
https://www.ncbi.nlm.nih.gov/pubmed/35465025
http://dx.doi.org/10.3389/fgeed.2022.843885

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