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Seamless Gene Correction in the Human Cystic Fibrosis Transmembrane Conductance Regulator Locus by Vector Replacement and Vector Insertion Events

Background: Gene correction via homology directed repair (HDR) in patient-derived induced pluripotent stem (iPS) cells for regenerative medicine are becoming a more realistic approach to develop personalized and mutation-specific therapeutic strategies due to current developments in gene editing and...

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Detalles Bibliográficos
Autores principales:	Suzuki, Shingo, Chosa, Keisuke, Barillà, Cristina, Yao, Michael, Zuffardi, Orsetta, Kai, Hirofumi, Shuto, Tsuyoshi, Suico, Mary Ann, Kan, Yuet W., Sargent, R. Geoffrey, Gruenert, Dieter C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genome Editing
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019469/ https://www.ncbi.nlm.nih.gov/pubmed/35465025 http://dx.doi.org/10.3389/fgeed.2022.843885

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