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Dichotomous feedback: a signal sequestration-based feedback mechanism for biocontroller design
We introduce a new design framework for implementing negative feedback regulation in synthetic biology, which we term ‘dichotomous feedback’. Our approach is different from current methods, in that it sequesters existing fluxes in the process to be controlled, and in this way takes advantage of the...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019519/ https://www.ncbi.nlm.nih.gov/pubmed/35440202 http://dx.doi.org/10.1098/rsif.2021.0737 |