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Gasdermin E: A Prospective Target for Therapy of Diseases

Gasdermin E (GSDME) is a member of the gasdermin protein family, which mediates programmed cell death including apoptosis and pyroptosis. Recently, it was suggested that GSDME is activated by chemotherapeutic drugs to stimulate pyroptosis of cancer cells and trigger anti-tumor immunity, which is ide...

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Detalles Bibliográficos
Autores principales: Liao, Xiu-Xiu, Dai, Yong-Zhao, Zhao, Yao-Zhong, Nie, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019550/
https://www.ncbi.nlm.nih.gov/pubmed/35462927
http://dx.doi.org/10.3389/fphar.2022.855828