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Spironolactone alleviates myocardial fibrosis via inhibition of Ets-1 in mice with experimental autoimmune myocarditis

Spironolactone improves cardiac structure, function and prognosis in patients with heart failure and delays the progression of cardiac fibrosis. However, the exact underlying mechanism of this process remains to be elucidated. The present study therefore aimed to explore the protective effect and un...

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Detalles Bibliográficos
Autores principales: Wang, Wen-Ke, Wang, Ben, Cao, Xue-Hu, Liu, Yu-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019666/
https://www.ncbi.nlm.nih.gov/pubmed/35495592
http://dx.doi.org/10.3892/etm.2022.11296