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Nuclear transfer system for the direct induction of embryonic transcripts from intra- and cross-species nuclei using mouse 4-cell embryos

Reprogramming of somatic nuclei toward the embryonic state has been studied using nuclear transfer (NT) to an oocyte at the metaphase II (MII) stage. In this NT, a somatic nucleus transplanted into an MII oocyte of the same species undergoes DNA replication and cell division before activating embryo...

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Detalles Bibliográficos
Autores principales: Tomikawa, Junko, Penfold, Christopher A., Hatakeyama, Rena, Miyamoto, Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019708/
https://www.ncbi.nlm.nih.gov/pubmed/35463476
http://dx.doi.org/10.1016/j.xpro.2022.101284