Optogenetic control of the Bicoid morphogen reveals fast and slow modes of gap gene regulation

Developmental patterning networks are regulated by multiple inputs and feedback connections that rapidly reshape gene expression, limiting the information that can be gained solely from slow genetic perturbations. Here we show that fast optogenetic stimuli, real-time transcriptional reporters, and a...

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Detalles Bibliográficos
Autores principales: Singh, Anand P., Wu, Ping, Ryabichko, Sergey, Raimundo, João, Swan, Michael, Wieschaus, Eric, Gregor, Thomas, Toettcher, Jared E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019726/
https://www.ncbi.nlm.nih.gov/pubmed/35320726
http://dx.doi.org/10.1016/j.celrep.2022.110543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019726/
https://www.ncbi.nlm.nih.gov/pubmed/35320726
http://dx.doi.org/10.1016/j.celrep.2022.110543

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