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Optogenetic control of the Bicoid morphogen reveals fast and slow modes of gap gene regulation
Developmental patterning networks are regulated by multiple inputs and feedback connections that rapidly reshape gene expression, limiting the information that can be gained solely from slow genetic perturbations. Here we show that fast optogenetic stimuli, real-time transcriptional reporters, and a...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019726/ https://www.ncbi.nlm.nih.gov/pubmed/35320726 http://dx.doi.org/10.1016/j.celrep.2022.110543 |