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miR-654-5p Contributes to the Activation and Proliferation of Hepatic Stellate Cells by Targeting RXRα

Liver fibrosis (LF) is a major disease that threatens human health. Hepatic stellate cells (HSCs) contribute directly to LF via extracellular matrix (ECM) secretion. Moreover, RXRα is an important nuclear receptor that plays a key regulatory role in HSC activation. Meanwhile, microRNAs (miRNAs) have...

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Detalles Bibliográficos
Autores principales: Ma, Heming, Wang, Xiaomei, Liu, Xu, Wang, Chang, Gao, Xiuzhu, Niu, Junqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019757/
https://www.ncbi.nlm.nih.gov/pubmed/35465330
http://dx.doi.org/10.3389/fcell.2022.841248