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WT1: The Hinge Between Anemia Correction and Cancer Development in Chronic Kidney Disease

Hypoxia-inducible factor-prolyl hydroxylase inhibitors (HIF-PHIs) emerge as promising agents to treat anemia in chronic kidney disease (CKD) but the major concern is their correlated risk of cancer development and progression. The Wilms’ tumor gene, WT1, is transcriptionally regulated by HIF and is...

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Detalles Bibliográficos
Autores principales: Lee, Wen-Chin, Chiu, Chien-Hua, Chu, Tian-Huei, Chien, Yu-Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019781/
https://www.ncbi.nlm.nih.gov/pubmed/35465313
http://dx.doi.org/10.3389/fcell.2022.876723