Co‐occurrence of CDKN2A/B and IFN‐I homozygous deletions correlates with an immunosuppressive phenotype and poor prognosis in lung adenocarcinoma

Homozygous deletion (HD) of CDKN2A and CDKN2B (CDKN2A/B (HD)) is the most frequent copy‐number variation (CNV) in lung adenocarcinoma (LUAD). CDKN2A/B (HD) has been associated with poor outcomes in LUAD; however, the mechanisms of its prognostic effect remain unknown. We analyzed genome, transcripto...

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Detalles Bibliográficos
Autores principales: Peng, Yuan, Chen, Yonghong, Song, Mengmeng, Zhang, Xiaoyue, Li, Pansong, Yu, Xian, Huang, Yusheng, Zhang, Ni, Ji, Liyan, Xia, Lei, Xia, Xuefeng, Yi, Xin, Tan, Benxu, Yang, Zhenzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019898/
https://www.ncbi.nlm.nih.gov/pubmed/35253368
http://dx.doi.org/10.1002/1878-0261.13206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019898/
https://www.ncbi.nlm.nih.gov/pubmed/35253368
http://dx.doi.org/10.1002/1878-0261.13206

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