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Clausena Harmandiana root extract attenuated cognitive impairments via reducing amyloid accumulation and neuroinflammation in Aβ(1-42)-induced rats

BACKGROUND: Alzheimer’s disease (AD) pathogenesis is associated with amyloid-β (Aβ)-induced neuroinflammation. In AD, the activation of microglia caused by Aβ accumulation is followed by the synthesis and release of pro-inflammatory cytokines, including interleukin-1β (IL-1β) and tumor necrosis fact...

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Detalles Bibliográficos
Autores principales: Nillert, Nutchareeporn, Boonyarat, Chantana, Welbat, Jariya Umka, Bunreungthong, Komsun, Puthongking, Ploenthip, Pannangrong, Wanassanun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019931/
https://www.ncbi.nlm.nih.gov/pubmed/35439990
http://dx.doi.org/10.1186/s12906-022-03591-4