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Alpha-1-antichymotrypsin as a novel biomarker for diagnosis, prognosis, and therapy prediction in human diseases

The glycoprotein alpha-1-antichymotrypsin (AACT), a serine protease inhibitor, is mainly synthesized in the liver and then secreted into the blood and is involved in the acute phase response, inflammation, and proteolysis. The dysregulation of AACT and its glycosylation levels are associated with tu...

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Detalles Bibliográficos
Autores principales: Jin, Yanxia, Wang, Weidong, Wang, Qiyun, Zhang, Yueyang, Zahid, Kashif Rafiq, Raza, Umar, Gong, Yongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019971/
https://www.ncbi.nlm.nih.gov/pubmed/35439996
http://dx.doi.org/10.1186/s12935-022-02572-4