Metacell-2: a divide-and-conquer metacell algorithm for scalable scRNA-seq analysis

Scaling scRNA-seq to profile millions of cells is crucial for constructing high-resolution maps of transcriptional manifolds. Current analysis strategies, in particular dimensionality reduction and two-phase clustering, offer only limited scaling and sensitivity to define such manifolds. We introduc...

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Detalles Bibliográficos
Autores principales: Ben-Kiki, Oren, Bercovich, Akhiad, Lifshitz, Aviezer, Tanay, Amos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019975/
https://www.ncbi.nlm.nih.gov/pubmed/35440087
http://dx.doi.org/10.1186/s13059-022-02667-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019975/
https://www.ncbi.nlm.nih.gov/pubmed/35440087
http://dx.doi.org/10.1186/s13059-022-02667-1

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